Why do we get certain diseases, whereas other diseases do not exist?In this book, Alon, one of the founders of systems biology, builds a foundation for systems medicine.Starting from basic laws, the book derives why physiological circuits are built the way they are. The circuits have fragilities that explain specific diseases and offer new strategies to treat them.By the end, the reader will be able to use simple and powerful mathematical models to describe physiological circuits. The book explores, in three parts, hormone circuits, immune circuits, and aging and age-related disease. It culminates in a periodic table of diseases.Alon writes in a style accessible to a broad range of readers - undergraduates, graduates, or researchers from computational or biological backgrounds. The level of math is friendly and the math can even be bypassed altogether. For instructors and readers who want to go deeper, the book includes dozens of exercises that have been rigorously tested in the classroom Read more

‘So staggering you go “whoa!” every few seconds’ Guardian‘Really impressive’ Eamonn Holmes, ITV This MorningA companion book to the critically acclaimed BBC series.The bestselling authors of Wonders of the Universe are back with another blockbuster, a groundbreaking exploration of our Solar System as it has never been seen before.Mercury, a lifeless victim of the Sun’s expanding power. Venus, once thought to be lush and fertile, now known to be trapped within a toxic and boiling atmosphere. Mars, the red planet, doomed by the loss of its atmosphere. Jupiter, twice the size of all the other planets combined, but insubstantial. Saturn, a stunning celestial beauty, the jewel of our Solar System. Uranus, the sideways planet and the first ice giant. Neptune, dark, cold and whipped by supersonic winds. Pluto, the dwarf planet, a frozen rock.Andrew Cohen and Professor Brian Cox take readers on a voyage of discovery, from the fiery heart of our Solar System, to its mysterious outer reaches. They touch on the latest discoveries that have expanded our knowledge of the planets, their moons and how they come to be, alongside recent stunning and mind-boggling NASA photography. Read more

A brilliant introductory guide to exploring the night sky, from the astronomers of the Royal Observatory Greenwich.Offering complete advice from the ground up, Stargazing is the perfect manual for beginners to astronomy – introducing the world of telescopes, planets, stars, dark skies and celestial maps.Discover how to tackle light pollution, how to stargaze with just your eyes, and what equipment is best for beginners.Astronomy experts Radmila Topalovic and Tom Kerss explain the best ways to plan your stargazing experience and the key things to look out for on specific dates throughout the year.With seasonal star charts, constellation charts and facts about our Solar System, Stargazing is packed of useful information and guidance for both the Northern and Southern Hemispheres.Bridging the gap between human curiosity and the need for scientific expertise, Stargazing allows a complete novice to understand our place in the cosmos and enjoy the beautiful and extraordinary wonders of the night sky.The perfect companion to the best-selling Guide to the Night Sky from Collins, Stargazing is a great way to get started in the fascinating world of astronomy.Download your free resource booklet to follow the star chart explanations on the Stargazing audiobook – visit collins.co.uk/stargazing-booklet Read more

A Brief History of Time for the 21st CenturyAt the heart of our galaxy lies a monster so deadly, not even light can escape its grasp. Its secrets lie waiting to be discovered. It’s time to explore our universe’s most mysterious inhabitantsBlack HolesAt the heart of the Milky Way lies a supermassive black hole 4 million times more massive than our Sun. A place where space and time are so warped that light is trapped if it ventures within 12 million km. According to Einstein, inside lies the end of time. According to 21st-century physics, the reality may be far more bizarre.Black holes lie where the most massive stars used to shine and at the edge of our current understanding. They are naturally occurring objects, the inevitable creations of gravity when too much matter collapses into not enough space. And yet, although the laws of nature predict them, they fail fully to describe them.Black holes are places in space and time where the laws of gravity, quantum physics and thermodynamics collide. Originally thought to be so intellectually troubling that they simply could not exist, it is only in the past few years that we have begun to glimpse a new synthesis; a deep connection between gravity and quantum information theory that describes a holographic universe in which space and time emerge from a network of quantum bits, and wormholes span the void.In this groundbreaking book, Professor Brian Cox and Professor Jeff Forshaw take you to the edge of our understanding of black holes; a scientific journey to the research frontier spanning a century of physics, from Einstein to Hawking and beyond, that ends with the startling conclusion that our world may operate like a giant quantum computer. Read more

Discover the wonders of the Universe with this complete introduction to observing and understanding the night sky. This practical guide explains and demystifies stargazing, teaching you to recognize different kinds of objects and showing you how they move through the sky over the course of the night and the year. It shows you how to understand and enjoy the cosmos, building your practical astronomy skills from the basics to more advanced techniques. Beginning with an explanation of the Universe itself - how big is it, what shape is it, how old is it, and will it end? - it then takes you on a tour around the night sky, building up your knowledge in simple stages. Practical advice begins with naked-eye observations, then illustrated step-by-step instructions show you how to set up and use binoculars and telescopes, and how to take your own pictures of the night sky. It also lets you take a closer look at the different objects you can view in the night sky, telling you how to train your eye to recognize basic patterns of stars (constellations) and how to tell planets apart from other celestial bodies, showing you how to observe them in an innovative step-by-step way. An atlas of the night sky is also included, with charts that can be used in both the northern and southern hemispheres throughout the year.Accessible, inspirational, and authoritative, Stargazing for Beginners will enthuse and inform anyone who wants to expand their knowledge of the night sky. Read more

"Tyson has told the story of our Universe magnificently in these 12 short chapters...This may have been written for people in a hurry, but I urge you to take your time. It will all be over far too soon." BBC Sky at Night There's no better guide through mind-expanding questions such as what the nature of space and time is, how we fit within the universe, and how the universe fits within us than Neil deGrasse Tyson. But today, few of us have time to contemplate the cosmos. So Tyson brings the universe down to Earth succinctly and clearly, with sparkling wit, in digestible chapters consumable any time and anywhere in the busy day. Astrophysics for People in a Hurry reveals just what you need to be fluent and ready for the next cosmic headlines: from the Big Bang to black holes, from quarks to quantum mechanics and from the search for planets to the search for life in the universe. Read more

Learn about the Big Bang theory, astrophysics and gravity in The Physics Book.Part of the fascinating Big Ideas series, this book tackles tricky topics and themes in a simple and easy to follow format. Learn about Physics in this overview guide to the subject, brilliant for beginners looking to learn and experts wishing to refresh their knowledge alike! The Physics Book brings a fresh and vibrant take on the topic through eye-catching graphics and diagrams to immerse yourself in. This captivating book will broaden your understanding of physics, with:- More than 100 ground-breaking ideas in this field of science- Packed with facts, charts, timelines and graphs to help explain core concepts- A visual approach to big subjects with striking illustrations and graphics throughout- Easy to follow text makes topics accessible for people at any level of understandingThe Physics Book is the perfect introduction to the science, aimed at adults with an interest in the subject and students wanting to gain more of an overview. Here you'll discover more than 90 of the most important laws and theories in the history of physics and the great minds behind them. If you've ever wondered exactly how physicists formulated and proved groundbreaking abstract concepts, this is the perfect book for you.Your Physics Questions, Simply ExplainedHow do magnets generate electricity? What is antimatter? Is time travel possible? If you thought it was difficult to learn the many laws and concepts of physics, The Physics Book presents key information in a clear layout. Learn about Pythagoras's observations on music, Galileo's experiments with spheres and Isaac Newton's theories of gravity and laws of motion with superb mind maps and step-by-step summaries.The Big Ideas SeriesWith millions of copies sold worldwide, The Physics Book is part of the award-winning Big Ideas series from DK. The series uses striking graphics along with engaging writing, making big topics easy to understand. Read more

RADIO 4 BOOK OF THE WEEKFINANCIAL TIMES 2023 BOOK OF THE YEARTHE TIMES SCIENCE BOOK OF THE YEAR: 'This beautifully written, sweeping guide shows how the deep movement of the seas have ruled our lives in unexpected ways over millennia.''The world needs a 'David Attenborough for physics' and Helen Czerski is a prime contender - she's brilliant, clear, passionate, modern and inspiring.' - Emma Freud, BBC Radio 4 Loose Ends'A dazzle of stories beautifully told...Outstanding ... Her readers will see the seas anew.'Horatio Clare, Telegraph'Excellent and important.' Spectator'Czerski is a wonderful writer ... Blue Machine really does change the way you see the world.' Daily Mail'In Helen Czerski's hands, the mechanical becomes magical. An instant classic.'Tristan Gooley, author of How to Read Water'Blue Machine is quite simply one of the best books I have ever read.'Dr George McGavin, zoologist, entomologist and broadcaster'A fascinating dive into the essential engine that drives our world.'Gaia Vince, science journalist, broadcaster and author of Nomad Century All of the Earth's ocean, from the equator to the poles, is a single engine powered by sunlight - a blue machine.Earth is home to a huge story that is rarely told - that of our ocean. Not the fish or the dolphins, but the massive ocean engine itself: what it does, why it works, and the many ways it has influenced animals, weather and human history & culture.In a book that will recalibrate our view of this defining feature of our planet, physicist Helen Czerski dives deep to illuminate the murky depths of the ocean engine, examining the messengers, passengers and voyagers that live in it, travel over it, and survive because of it. From the ancient Polynesians who navigated the Pacific by reading the waves to permanent residents of the deep such as the Greenland shark that can live for hundreds of years, she explains the vast currents, invisible ocean walls and underwater waterfalls that all have their place in the ocean's complex, interlinked system.Timely, elegant and passionately argued, Blue Machine presents a fresh perspective on what it means to be a citizen of an ocean planet. The understanding it offers is crucial to our future. Drawing on years of experience at the forefront of marine science, Helen Czerski captures the magnitude and subtlety of Earth's defining feature, showing us the thrilling extent to which we are at the mercy of this great engine....................................'Helen Czerski weaves together physics and biology, history and science, in a beautifully poetic way.'Professor Alice Roberts Read more

THE PHENOMENAL BESTSELLER FROM THE AUTHOR OF WHITE HOLESOne of the Best Books of the 21st Century according to The Guardian'The perfect antidote to the fluff and nonsense around right now. Learn how the world is and how you might just fit in' Simon MayoThese seven short lessons guide us, with simplicity and clarity, through the scientific revolution that shook physics in the twentieth century and still continues to shake us today. In this mind-bending overview of modern physics, Carlo Rovelli explains Einstein's theory of general relativity, quantum mechanics, black holes, the complex architecture of the universe, elementary particles, gravity, and the nature of the mind. Not since Richard Feynman's celebrated Six Easy Pieces has physics been so vividly, intelligently and entertainingly revealed.Translated by Simon Carnell and Erica Segre Read more

A journey through the otherworldly science behind Christopher Nolan’s award-winning film, Interstellar, from executive producer and Nobel Prize-winning physicist Kip Thorne.Interstellar, from acclaimed filmmaker Christopher Nolan, takes us on a fantastic voyage far beyond our solar system. Yet in The Science of Interstellar, Kip Thorne, the Nobel prize-winning physicist who assisted Nolan on the scientific aspects of Interstellar, shows us that the movie’s jaw-dropping events and stunning, never-before-attempted visuals are grounded in real science. Thorne shares his experiences working as the science adviser on the film and then moves on to the science itself. In chapters on wormholes, black holes, interstellar travel, and much more, Thorne’s scientific insights ― many of them triggered during the actual scripting and shooting of Interstellar ― describe the physical laws that govern our universe and the truly astounding phenomena that those laws make possible.Interstellar and all related characters and elements are trademarks of and © Warner Bros. Entertainment Inc. (s14).200 colour illustrations Read more

THE PHENOMENAL BESTSELLER'Honestly I cannot recommend it too strongly... one of the fastest selling science titles of all time because it is so clear' Jeremy Vine, BBC Radio 2'There's a book I've been carrying around like a small Bible, Seven Brief Lessons on Physics' - Benedict CumberbatchEverything you need to know about modern physics, the universe and your place in the world in seven enlightening lessonsThese seven short lessons guide us, with simplicity and clarity, through the scientific revolution that shook physics in the twentieth century and still continues to shake us today. In this beautiful and mind-bending introduction to modern physics, Carlo Rovelli explains Einstein's theory of general relativity, quantum mechanics, black holes, the complex architecture of the universe, elementary particles, gravity, and the nature of the mind. In under eighty pages, readers will understand the most transformative scientific discoveries of the twentieth century and what they mean for us. Not since Richard Feynman's celebrated best-seller Six Easy Pieces has physics been so vividly, intelligently and entertainingly revealed. Read more

Top ten Sunday Times Bestseller‘Engaging, ambitious and creative’ GuardianWhere are we? Are we alone? Who are we? Why are we here? What is our future?Human Universe tackles some of the greatest questions that humans have asked to try and understand the very nature of ourselves and the Universe in which we live.Through the endless leaps of human minds, it explores the extraordinary depth of our knowledge today and where our curiosity may lead us in the future. With groundbreaking insight it reveals how time, physics and chemistry came together to create a creature that can wonder at its own existence, blessed with an unquenchable thirst to discover not just where it came from, but how it can think, where it is going and if it is alone.Accompanies the acclaimed BBC TV series. Read more

A Brief History of Time for the 21st CenturyAt the heart of our galaxy lies a monster so deadly, not even light can escape its grasp. Its secrets lie waiting to be discovered. It’s time to explore our universe’s most mysterious inhabitantsBlack HolesAt the heart of the Milky Way lies a supermassive black hole 4 million times more massive than our Sun. A place where space and time are so warped that light is trapped if it ventures within 12 million km. According to Einstein, inside lies the end of time. According to 21st-century physics, the reality may be far more bizarre.Black holes lie where the most massive stars used to shine and at the edge of our current understanding. They are naturally occurring objects, the inevitable creations of gravity when too much matter collapses into not enough space. And yet, although the laws of nature predict them, they fail fully to describe them.Black holes are places in space and time where the laws of gravity, quantum physics and thermodynamics collide. Originally thought to be so intellectually troubling that they simply could not exist, it is only in the past few years that we have begun to glimpse a new synthesis; a deep connection between gravity and quantum information theory that describes a holographic universe in which space and time emerge from a network of quantum bits, and wormholes span the void.In this groundbreaking book, Professor Brian Cox and Professor Jeff Forshaw take you to the edge of our understanding of black holes; a scientific journey to the research frontier spanning a century of physics, from Einstein to Hawking and beyond, that ends with the startling conclusion that our world may operate like a giant quantum computer. Read more

Professor Stephen Hawking is generally considered to have been one of the world's greatest thinkers. Here, his phenomenal bestseller A Brief History of Time is illustrated to bring his theories to life in a clear, captivating and visually engaging way.'This book marries a child's wonder to a genius's intellect. We journey into Hawking's universe, while marvelling at his mind' - The Sunday Times'Stephen Hawking can explain the complexities of cosmological physics with an engaging combination of clarity and wit...' - Observer'Exceptional writing explaining the mysteries and beauty of our universe. The book is very fascinating and highly enjoyable. Highly recommended' - ***** Reader review'This book is mind blowing' - ***** Reader review'A masterpiece' - ***** Reader review********************************************************************************************Was there a beginning of time? Could time run backwards? Is the universe infinite or does it have boundaries?These are just some of the questions considered in the internationally acclaimed masterpiece by the world-renowned physicist Professor Stephen Hawking.It begins by reviewing the great theories of the cosmos from Newton to Einstein, before delving into the secrets which still lie at the heart of space and time, from the Big Bang to black holes, via spiral galaxies and strong theory. To this day A Brief History of Time remains a staple of the scientific canon, and its succinct and clear language continues to introduce millions to the universe and its wonders.In this edition, Professor Hawking explains his complex theories through a fresh visual dimension. Over 150 stunning colour illustrations have been specially commissioned for this purpose to help the reader understand what have become popular mythic images of our century, but which nonetheless remain difficult, abstract ideas to grasp.This stunning gift edition also includes a new appendix with updates to the text and tributes to Stephen Hawking. Read more

'This is the best book on the subject that I have read, it's brilliant, wide ranging, easy to read, doesn't use tech jargon and its been designed to help you learn about the subject, not just read a book.' - Amazon 5 star review ⭐⭐⭐⭐⭐ 'Excellent for beginners like myself.' - Amazon 5 star review ⭐⭐⭐⭐⭐What processes and physical materials have shaped the planet we live on? Why do earthquakes happen? And what can geology teach us about contemporary issues such as climate change?From volcanoes and glaciers to fossils and rock formations, this user-friendly book gives a structured and thorough overview of the geology of planet Earth and beyond. Geology: A Complete Introduction outlines the basics in clear English, and provides added-value features like a glossary of the essential jargon terms, links to useful websites, and examples of questions you might be asked in a seminar or exam.Topics covered include the Earth's structure, earthquakes, plate tectonics, volcanoes, igneous intrusions, metamorphism, weathering, erosion, deposition, deformation, physical resources, past life and fossils, the history of the Earth, Solar System geology, and geological fieldwork. There are useful appendices on minerals, rock names and geological time.Whether you are preparing for an essay, studying for an exam or simply want to enrich your hobby or expand your knowledge, Geology: A Complete Introduction is your essential guide. Read more

Was there a beginning of time? Could time run backwards? Is the universe infinite or does it have boundaries? These are just some of the questions considered in the internationally acclaimed masterpiece by the world renowned physicist - generally considered to have been one of the world's greatest thinkers.It begins by reviewing the great theories of the cosmos from Newton to Einstein, before delving into the secrets which still lie at the heart of space and time, from the Big Bang to black holes, via spiral galaxies and strong theory. To this day A Brief History of Time remains a staple of the scientific canon, and its succinct and clear language continues to introduce millions to the universe and its wonders.This new edition includes updates from Stephen Hawking with his latest thoughts about the No Boundary Proposal and offers new information about dark energy, the information paradox, eternal inflation, the microwave background radiation observations, and the discovery of gravitational waves.It was published in tandem with the app, Stephen Hawking's Pocket Universe.'This book marries a child's wonder to a genius's intellect. We journey into Hawking's universe while marvelling at his mind.' The Sunday Times Read more

Marvel at the wonders of the Universe, from stars and planets to black holes and nebulae, in this exploration of our Solar System and beyond.Universe opens with a look at astronomy and the history of the Universe, using 3D artworks to provide a comprehensive grounding in the fundamental concepts of astronomy, including the basic techniques of practical astronomy.The core of the book is a tour of the cosmos covering the Solar System, the Milky Way, and galaxies beyond our own. Explanatory pages introduce different celestial phenomena, such as galaxies, and are followed by catalogues that profile the most interesting and important examples.A comprehensive star atlas completes the picture, with entries on each of the 88 constellations and a monthly sky guide showing the night sky as it appears throughout the year as viewed from both the northern and southern hemispheres. Read more

Sunday Times BestsellerHow did life on Earth begin? What is the nature of space and time? What are the chances that we will discover life on other worlds?Think you know our planet?Think again.Forces of Nature takes you from the mid-Atlantic ridge in Iceland, the volcanoes of Indonesia and the precipitous cliffs in Nepal, to the manatees off the coast of Florida and the northern lights of the Arctic, in search of the fundamental laws that govern our world.These universal laws shape everything, from the structure of snowflakes to the elegant spirals of the galaxies. By seeking to understand the everyday world – the colours, structure, behaviour and history of our home – we can step beyond the everyday and approach the Universe beyond. Read more

‘So staggering you go “whoa!” every few seconds’ Guardian‘Really impressive’ Eamonn Holmes, ITV This MorningA companion book to the critically acclaimed BBC series.The bestselling authors of Wonders of the Universe are back with another blockbuster, a groundbreaking exploration of our Solar System as it has never been seen before.Mercury, a lifeless victim of the Sun’s expanding power. Venus, once thought to be lush and fertile, now known to be trapped within a toxic and boiling atmosphere. Mars, the red planet, doomed by the loss of its atmosphere. Jupiter, twice the size of all the other planets combined, but insubstantial. Saturn, a stunning celestial beauty, the jewel of our Solar System. Uranus, the sideways planet and the first ice giant. Neptune, dark, cold and whipped by supersonic winds. Pluto, the dwarf planet, a frozen rock.Andrew Cohen and Professor Brian Cox take readers on a voyage of discovery, from the fiery heart of our Solar System, to its mysterious outer reaches. They touch on the latest discoveries that have expanded our knowledge of the planets, their moons and how they come to be. Read more

A BOOK OF THE YEAR ACCORDING TO THE FINANCIAL TIMES * SUNDAY TELEGRAPH * NEW STATESMAN * NEW SCIENTIST'A miniature masterpiece by one of the most entertaining scientists on the planet' Evening Standard‘Everyone’s talking about White Holes’ Daily MailA mesmerizing trip to the strange new world of white holes, from Carlo Rovelli, the bestselling author of Seven Brief Lessons on PhysicsLet us journey into the heart of a black hole. Let us slip beyond its boundary, the horizon, and tumble - on and on - down this crack in the universe. As we plunge, we'll see geometry fold, we'll feel the equations draw tight around us. Eventually, we'll pass it: the remains of a star, deep and dense and falling further far. And then - the bottom. Where time and space end, and the white hole is born . . . With lightness and magic, here Carlo Rovelli traces the ongoing adventure of his own cutting-edge research, of the uncertainty and joy of going where we've not yet been. Guiding us to the edge of theory and experiment, he invites us to go beyond, to experience the fever and the disquiet of science. Here is the extraordinary life of a white hole. Read more